2024 Ddp ic50

Ddp ic50

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August undefined, 2024

WebNational Center for Biotechnology Information WebThe NSCLC tissues from patients with progressive disease (PD) had even lower GAS5 expression. GAS5 knockdown increased DDP IC50 of A549 cells, while GAS5 …

Circular RNA hsa_circ_0000277 promotes tumor progression and DDP …

WebAug 13, 2010 · Curcumin could significantly inhibit A549 and A549/DDP cells growth in MTT assays, and the inhibition ratio was markedly increased in a dose- and time-dependent manner (Fig. 1A).The IC50 of curcumin at 48 h were 16.28 ± 1.4 μmol/L for A549 cells and 18.06 ± 1.9 μmol/L for A549/DDP cells (Fig. 1B), which were not significantly different (P … Web1003-1856-ND. Manufacturer. ITT Cannon, LLC. Manufacturer Product Number. DDM-50P. Description. CONN D-SUB PLUG 50POS PNL MNT. Manufacturer Standard Lead Time. … havanese ornament

Cancer‐associated fibroblast‐derived exosomal microRNA‐20a …

WebThe 50 % inhibitory concentration (IC50) of cisplatin in A549 and A549/DDP cells 48 h after drug treatment Source publication +4 RNA interferences targeting the Fanconi … WebJan 28, 2024 · It was noticed that DDP-resistant cells Exos promoted Linc00852 level, increased IC50 value of DDP, and stimulated the growth of MGC-803 and BGC-823 cells. But, Exos carrying inhibited Linc00852 suppressed the IC50 value of DDP and the growth of recipient cells (Fig. 4A–E). Obviously, Linc00852 from DDP-resistant GC cell-derived … WebTerms and conditions. IC50 of DDP and the expression level of miR-1236-3p in A549 and A549/DDP cells. (A) The concentration of 20 μg/ml-DDP was added to verify the IC50 values in A549 and A549 ... havanese owners club

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Circular RNA hsa_circ_0096157 contributes to cisplatin ... - Springer

WebNov 9, 2024 · The IC50 of NSCLC cells to DDP was measured by CCK-8 assay. NSCLC cell proliferation and apoptosis were observed by clone formation assay and flow cytometry. The content of m6A in total RNA in tissues and cells of NSCLC patients was detected using m6A Methylation Quantification Kit. The expressions of DGCR8-bound pri-miR-19a and m6A … WebAug 27, 2024 · Meanwhile, the IC50 values of DDP and sodium butyrate in the HGC-27 cells at 24 h were about 4 µg/ml and 10 mM. Then, the HGC-27 and SGC-7901 cells were exposed to combinations of cisplatin and … havanese olive branch msWebNov 18, 2024 · Compared with the DDP group, the IC50 value of DDP in the FOXO1-overexpressing NPC cells was significantly reduced when combined with CB (Fig. 5a). Next, we observed that the survival time of nude ... boreland loan kirkcaldy

"WebMar 22, 2024 · The drug’s IC 50 values indicated that the cells had acquired a stable CDDP-resistance phenotype, with the IC 50 values of the A549/DDP cells remaining … " - Ddp ic50

Ddp ic50

Linc00852 from cisplatin-resistant gastric cancer cell ... - Springer

WebFeb 3, 2024 · MTT assay showed that compared with the DDP + HCT116 and DDP + HCT116 + NFs groups or DDP + LoVo and DDP + LoVo + CAFs groups, the cell viability and IC50 value of CAFs co-cultured group were obviously increased, indicating that CAFs significantly improved the resistance of HCT116 or LoVo cells to DDP (Fig. 1C and … WebGemcitabine (LY-188011, NSC 613327) HCl is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, …

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WebCisplatin (DDP) is the most commonly used platinum anticancer drug. It was launched in the United States in 1978 and became the first-line platinum drug to treat a variety of malignant tumors ( Dasari and Tchounwou, 2014 ). However, the side effects of DDP reduce the patients’ quality of life and treatment compliance ( Breen et al., 2024 ). WebDDP has gradually become the standard chemotherapy method for chronic lung adenocarcinoma and postoperative grade II and III lung adenocarcinoma.8Although lung …

WebAug 6, 2024 · The half-maximal inhibitory concentration (IC50) of A549 and A549/DDP cells was determined using CCK-8 assay. Further, circRNA profiles and differentially expressed genes in A549 and A549/DDP cells were characterized by deep sequencing and cell proliferation was measured using MTS assay. Cell cycle progression was analyzed using … WebSep 30, 2024 · Cisplatin (DDP) is a key drug for ESCC treatment, but the presence of chemotherapy resistance limits the use of DDP. To enhance chemosensitivity to DDP is …

WebJul 20, 2024 · The viability (B and C) and DDP IC50 values (D) for NSCLC cell lines treated as in (A) were measured. The proliferation (E and F), colony formation (G and H) and Hoechst staining (I and J) results for NSCLC cell lines treated as in (A). (K and L) Western blotting was used to assess PI3K-p85, PI3K-p100, PI3K, pAKT and AKT expression in … WebThe IC50 values indicated that the remarkable compounds 7a (IC50 = 16.80 μM) and 7c (IC50 = 16.48 μM) had better inhibition for tumor cell A-549 than positive control DDP (IC50 = 20.62 μM). It should be noted that these transformations may provide a new strategy to derive natural products and discover new drugs.

WebAmphenol ICC (FCI) Manufacturer Product Number. DDM50P. Description. CONN D-SUB PLUG 50P SLDR CUP. Manufacturer Standard Lead Time. 11 Weeks. Detailed …

WebDDMA-50P. Digi-Key Part Number. 1003-1757-ND. Manufacturer. ITT Cannon, LLC. Manufacturer Product Number. DDMA-50P. Description. CONN D-SUB PLG 50P PNL … havanese of americaWebJun 8, 2024 · The IC 50 of OVCAR3/DDP and OVCAR3 cells were 122.30±2.83 and 66.08±5.25, respectively, and the index (RI) of OVCAR3/DDP cells was 1.87 ( Fig. 1C ). These results indicated that OVCAR3/DDP cells had increased resistance to cisplatin compared with OVCAR3 cells. Figure 1. Establishment of the cisplatin-resistant cell line … boreland hillWebDDP with IC50 of 57.7 and 86.2 μM was obtained for A549 cells with empty vector or USP14 expression vector transduction, respectively (Figure 2B). Moreover, apoptosis rates were higher in A549/DDP cells with relatively low USP14 expression compared with the rates in control cells (siNC) (Figure 2C,E ). boreland farming partnershipWebIC50 of DDP and the expression level of miR-1236-3p in A549 and A549/DDP cells. (A) The concentration of 20 μg/ml-DDP was added to verify the IC50 values in A549 and … boreland motteWebIn A549/DDP cells, GAS5 showed the similar effect as 3-MA in reducing DPP IC50 and promoting DDP-induced apoptosis and also presented synergic effect with 3-MA. CONCLUSIONS: GAS5 downregulation is associated with cisplatin resistance in NSCLC. GAS5 can inhibit autophagy and therefore enhance cisplatin sensitivity in NSCLC cells. … boreland hotel inverkeithingWebNov 13, 2024 · The DDP IC50 values for DDP‑resistant MGC803/DDP cells were greater than those for MGC803 cells. Furthermore, MGC803/DDP cells exhibited increased levels of viability, migration and invasion, and decreased levels of apoptosis and DNA damage during DDP treatment. Knockdown of RAP2A expression significantly promoted MGC803/DDP … havanese photo galleryWebMay 6, 2024 · DDP-resistant ovarian cancer cells possess enhanced metastatic activity and arachidonic acid metabolism. a The procedure for the induction of DDP-resistant SKOV3 cells (upper panel); IC50 and the cell viabilities of SKOV3 and SKOV3-R with different concentrations of DDP treatment (lower panel). b, c The mRNA ( b) and protein ( c) … boreland pss